Exhibit 16.1

Securities and Exchange Commission

100 First Street, N.E.

Washington, D.C. 20549

Ladies and Gentlemen:

We were previously independent accountants for Mustang Bio, Inc. (the “Company”). On September 29, 2016, our appointment as the Company’s independent accountants was terminated. We have read the Company’s statements included under item 4 of its Current Report on Form 8-K dated on or about October 5, 2016, and we agree with the statements set forth therein insofar as such comments relate to us.