Exhibit 31.1

MUSTANG BIO, INC.

CERTIFICATION PURSUANT TO

SECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I, Manuel Litchman, M.D., President and Chief Executive Officer (Principal Executive Officer), certify that:

	(1)	I have reviewed this Quarterly Report on Form 10-Q of Mustang Bio, Inc. (the “Registrant”);

	(2)	Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

November 14, 2017	By:	/s/ Manuel Litchman
		Manuel Litchman, M.D., President and
		Chief Executive Officer
		(Principal Executive Officer)