Annual report pursuant to Section 13 and 15(d)

Subsequent Events (Details Textual)

v3.7.0.1
Subsequent Events (Details Textual) - USD ($)
 1 Months Ended 10 Months Ended 12 Months Ended
Mar. 13, 2017
Mar. 17, 2017
Feb. 28, 2017
Feb. 17, 2017
Jan. 31, 2017
Jan. 02, 2017
Sep. 30, 2016
Mar. 17, 2015
Dec. 31, 2015
Dec. 31, 2016
Dec. 31, 2015
Subsequent Event [Line Items]                      
Payments of Stock Issuance Costs                   $ 4,090,000 $ 0
Stock Issued During Period, Value, Issued for Services                 $ 147,000 $ 862,000  
City Of Hope [Member]                      
Subsequent Event [Line Items]                      
Share Price               $ 0.147      
Payment Of Upfront Fees               $ 2,000,000      
Private Placement [Member]                      
Subsequent Event [Line Items]                      
Stock Issued During Period, Shares, New Issues             10,000        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights             2,500        
Class of Warrant or Right, Exercise Price of Warrants or Rights             $ 8.50        
Warrant Purchase Price Per Unit             $ 65,000        
Warrants Issued             191,483        
National Holdings Corporation [Member] | Private Placement [Member]                      
Subsequent Event [Line Items]                      
Percentage Of Placement Agent Fee             10.00%        
Percentage Of Shares Issued To Placement Agent             10.00%        
Subsequent Event [Member]                      
Subsequent Event [Line Items]                      
Warrants Issued         2,134,193            
Subsequent Event [Member] | City Of Hope [Member]                      
Subsequent Event [Line Items]                      
Revenue Recognition Milestone Method Payments Due       $ 125,000              
Payments for Other Fees       125,000              
Shares Issued, Price Per Share     $ 5.73                
Subsequent Event [Member] | City Of Hope [Member] | Licensing Agreements [Member]                      
Subsequent Event [Line Items]                      
Stock Issued During Period, Shares, Issued for Services     293,588                
Share Price     $ 5.73                
Stock Issued During Period, Value, Issued for Services     $ 1,700,000                
Subsequent Event [Member] | City Of Hope [Member] | A&R CD123 License [Member]                      
Subsequent Event [Line Items]                      
Revenue Recognition Milestone Method Payments Due       14,500,000              
Subsequent Event [Member] | City Of Hope [Member] | A&R IL-13 License [Member]                      
Subsequent Event [Line Items]                      
Revenue Recognition Milestone Method Payments Due       $ 14,500,000              
Subsequent Event [Member] | Unregistered Common Stock [Member]                      
Subsequent Event [Line Items]                      
Stock Issued During Period, Shares, New Issues         8,536,774            
Subsequent Event [Member] | Private Placement [Member]                      
Subsequent Event [Line Items]                      
Stock Issued During Period, Shares, New Issues         10,000            
Class of Warrant or Right, Number of Securities Called by Warrants or Rights         2,500            
Class of Warrant or Right, Exercise Price of Warrants or Rights         $ 8.50            
Warrant Purchase Price Per Unit         $ 65,000            
Warrant Expiration Term         5 years            
Subsequent Event [Member] | National Holdings Corporation [Member] | Private Placement [Member]                      
Subsequent Event [Line Items]                      
Proceeds from Issuance of Private Placement         $ 55,500,000            
Payments of Stock Issuance Costs         $ 5,500,000            
Percentage Of Placement Agent Fee         10.00%            
Warrants Issued         853,667            
Percentage Of Shares Issued To Placement Agent         10.00%            
Subsequent Event [Member] | University of California [Member] | UCLA License [Member]                      
Subsequent Event [Line Items]                      
Payment Of Upfront Fees   $ 200,000                  
Subsequent Event [Member] | Caribe BioAdvisors, LLC [Member]                      
Subsequent Event [Line Items]                      
Payments for Other Fees           $ 60,000          
Subsequent Event [Member] | Fortress Biotech, Inc [Member]                      
Subsequent Event [Line Items]                      
Stock Issued During Period, Shares, Issued for Services 767,264                    
Shares Issued, Price Per Share $ 5.73