Annual report pursuant to Section 13 and 15(d)

License, Clinical Trial and Sponsored Research Agreements (License Agreements) (Details)

v3.22.1
License, Clinical Trial and Sponsored Research Agreements (License Agreements) (Details) - USD ($)
 12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired $ 5,842,000 $ 10,064,000
License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired 5,842,000 10,064,000
CSL Behring (Calimmune) [Member] | License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired 30,000 170,000
Leiden University Medical Centre [Member] | License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired 350,000 0
Mayo Clinic [Member] | License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired 750,000 0
SIRION Biotech [Member] | License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired 0 117,000
Fortress Biotech, Inc [Member] | License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired 4,212,000 7,577,000
CD123 (MB-102) [Member] | City of Hope National Medical Center ("COH") [Member] | License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired 250,000 334,000
CS1 (MB-104) [Member] | City of Hope National Medical Center ("COH") [Member] | License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired 0 200,000
IL13Ra2 (MB-101) [Member] | City of Hope National Medical Center ("COH") [Member] | License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired 0 333,000
Spacer [Member] | City of Hope National Medical Center ("COH") [Member] | License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired 0 333,000
PSCA (MB-105) [Member] | City of Hope National Medical Center ("COH") [Member] | License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired 250,000 200,000
HER2 (MB 103) [Member] | City of Hope National Medical Center ("COH") [Member] | License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired 0 500,000
CD20 (MB-106) [Member] | Fred Hutchinson Cancer Research Center [Member] | License Agreements [Member]    
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]    
Research and development for licenses acquired $ 0 $ 300,000