Quarterly report pursuant to Section 13 or 15(d)

License, Clinical Trial and Sponsored Research Agreements

v3.19.1
License, Clinical Trial and Sponsored Research Agreements
3 Months Ended
Mar. 31, 2019
License Agreement Disclosure [Abstract]  
License Agreement Disclosure [Text Block]
Note 3 - License, Clinical Trial and Sponsored Research Agreements
 
Research and Development Expenses - All Licenses
 
For the three months ended March 31, 2019 and 2018, the Company recorded the following expense in research and development for licenses acquired:
 
 
 
For the three months ended March 31,
 
($ in thousands)
 
2019
 
 
2018
 
City of Hope
 
 
 
 
 
 
CD123
 
$ 250
 
 
$ -
 
Manufacturing
 
 
-
 
 
 
75
 
Nationwide Children's Hospital - C134
 
 
200
 
 
 
-
 
Total
 
$
450
 
 
$
75
 
 
License Agreements
 
Nationwide Children’s Hospital
 
In February 2019, Mustang announced that it partnered and entered into an exclusive worldwide license agreement with Nationwide Children’s Hospital (“Nationwide”) to develop
their C134
oncolytic virus (MB-108) for the treatment of glioblastoma multiforme (“GBM”). Mustang intends to combine
MB-108
with MB-101 (
IL13Rα2-
specific CAR T) to potentially enhance efficacy in treating GBM. The Company paid $0.2 million in consideration for the license to exclusive, worldwide rights to develop and commercialize products that incorporate data, know-how and/or
MB-108
that were developed at Nationwide. Additional payments are due to Nationwide upon achievement of development and commercialization milestones totaling $152.8 million. Royalty payments in the low-single digits are due on net sales of licensed products.
 
Research and Development Expenses - Sponsored Research and Clinical Trial Agreements
 
For the three months ended March 31, 2019 and 2018, the Company recorded the following expense in research and development for sponsored research and clinical trial agreements:
 
 
 
For the three months ended March 31,
 
 
 
2019
 
 
2018
 
($ in thousands)
 
 
 
 
 
 
City of Hope
 
$
500
 
 
$
500
 
City of Hope - CD123
 
 
303
 
 
 
150
 
City of Hope - IL13Rα2
 
 
342
 
 
 
360
 
City of Hope - Manufacturing
 
 
114
 
 
 
114
 
Fred Hutch - CD20
 
 
267
 
 
 
266
 
BIDMC - CRISPR
 
 
69
 
 
 
-
 
Total
 
$
1,595
 
 
$
1,390