Quarterly report pursuant to Section 13 or 15(d)

License, Clinical Trial and Sponsored Research Agreements (City of Hope - Sponsored Research and Clinical Trial Agreements) (Narrative) (Details)

v3.21.2
License, Clinical Trial and Sponsored Research Agreements (City of Hope - Sponsored Research and Clinical Trial Agreements) (Narrative) (Details)
1 Months Ended 3 Months Ended 6 Months Ended
Jul. 01, 2020
USD ($)
Jul. 03, 2017
USD ($)
Nov. 30, 2020
USD ($)
Oct. 31, 2020
USD ($)
Sep. 30, 2020
USD ($)
Jun. 30, 2020
USD ($)
Feb. 28, 2017
USD ($)
Mar. 31, 2015
USD ($)
installment
Jun. 30, 2021
USD ($)
Jun. 30, 2020
USD ($)
Jun. 30, 2021
USD ($)
Jun. 30, 2020
USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Research and development expense                 $ 10,902,000 $ 9,830,000 $ 22,520,000 $ 19,144,000
Sponsored Research and Clinical Trial Agreements [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Research and development expense                 1,260,000 2,816,000 3,102,000 4,166,000
Sponsored Research and Clinical Trial Agreements [Member] | City of Hope National Medical Center ("COH") [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable               $ 2,000,000.0        
Number of installments | installment               4        
Research and development expense                 0 0 0 500,000
Sponsored Research and Clinical Trial Agreements [Member] | CD123 Product or Process [Member] | City of Hope National Medical Center ("COH") [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Upfront fees paid             $ 19,450          
Contribution toward patient costs             200,000          
Contribution per patient             $ 97,490          
Agreement term             3 years          
Research and development expense                 21,000 65,000 226,000 296,000
Sponsored Research and Clinical Trial Agreements [Member] | IL13Ra2 Product [Member] | City of Hope National Medical Center ("COH") [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Upfront fees paid       $ 29,000     $ 9,300          
Milestones payable             200,000          
Additional milestone payments             $ 100,000          
Contribution per patient       100,000                
Agreement term             3 years          
Research and development expense                 279,000 234,000 793,000 326,000
Annual maintenance fee payable       200,000                
Sponsored Research and Clinical Trial Agreements [Member] | IL13Ra2 Product [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Contribution toward patient costs                     200,000  
Sponsored Research and Clinical Trial Agreements [Member] | CS1 Product or Process [Member] | City of Hope National Medical Center ("COH") [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable           $ 800,000            
Research and development expense                 197,000 770,000 372,000 770,000
Sponsored Research and Clinical Trial Agreements [Member] | CS1 Product or Process [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable           $ 2,400,000            
Sponsored Research and Clinical Trial Agreements [Member] | HER2 Product or Process [Member] | City of Hope National Medical Center ("COH") [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable         $ 29,375              
Research and development expense                 31,000 0 154,000 0
Sponsored Research and Clinical Trial Agreements [Member] | HER2 Product or Process [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable         $ 3,000,000.0              
Sponsored Research and Clinical Trial Agreements [Member] | PSCA Product or Process [Member] | City of Hope National Medical Center ("COH") [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable       33,000                
Research and development expense                 0 0 46,000 0
Sponsored Research and Clinical Trial Agreements [Member] | PSCA Product or Process [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable       $ 2,300,000                
Sponsored Research and Clinical Trial Agreements [Member] | CD20 Product or Process [Member] | Fred Hutchinson Cancer Research Center [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable   $ 5,300,000                    
Additional milestone payments     $ 800,000                  
Research and development expense                 327,000 189,000 998,000 716,000
Sponsored Research and Clinical Trial Agreements [Member] | ST. Jude - XSCID [Member] | St. Jude Children's Research Hospital [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Upfront fees paid $ 1,100,000                      
Research and development expense                 $ 176,000 $ 1,558,000 $ 280,000 $ 1,558,000