Quarterly report pursuant to Section 13 or 15(d)

License, Clinical Trial and Sponsored Research Agreements (City of Hope - Sponsored Research and Clinical Trial Agreements) (Narrative) (Details)

v3.21.2
License, Clinical Trial and Sponsored Research Agreements (City of Hope - Sponsored Research and Clinical Trial Agreements) (Narrative) (Details)
1 Months Ended 3 Months Ended 9 Months Ended
Jul. 01, 2020
USD ($)
Jul. 03, 2017
USD ($)
Nov. 30, 2020
USD ($)
Oct. 31, 2020
USD ($)
Sep. 30, 2020
USD ($)
Jun. 30, 2020
USD ($)
Feb. 28, 2017
USD ($)
Mar. 31, 2015
USD ($)
installment
Sep. 30, 2021
USD ($)
Sep. 30, 2020
USD ($)
Sep. 30, 2021
USD ($)
Sep. 30, 2020
USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Research and development expense                 $ 14,083,000 $ 7,987,000 $ 36,603,000 $ 27,131,000
Sponsored Research and Clinical Trial Agreements [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Research and development expense                 1,756,000 734,000 4,858,000 4,900,000
Sponsored Research and Clinical Trial Agreements [Member] | City of Hope National Medical Center ("COH") [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable               $ 2,000,000.0        
Number of installments | installment               4        
Research and development expense                 0 0 0 500,000
Sponsored Research and Clinical Trial Agreements [Member] | CD123 (MB-102) [Member] | City of Hope National Medical Center ("COH") [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Upfront fees paid             $ 19,450          
Contribution toward patient costs             200,000          
Contribution per patient             $ 97,490          
Agreement term             3 years          
Research and development expense                 24,000 48,000 250,000 344,000
Sponsored Research and Clinical Trial Agreements [Member] | IL13Ra2 (MB-101) [Member] | City of Hope National Medical Center ("COH") [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Upfront fees paid       $ 29,000     $ 9,300          
Milestones payable             200,000          
Additional milestone payments             $ 100,000          
Contribution per patient       100,000                
Agreement term             3 years          
Research and development expense                 199,000 96,000 992,000 422,000
Annual maintenance fee payable       200,000                
Sponsored Research and Clinical Trial Agreements [Member] | IL13Ra2 (MB-101) [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Contribution toward patient costs                     200,000  
Sponsored Research and Clinical Trial Agreements [Member] | CS1 (MB-104) [Member] | City of Hope National Medical Center ("COH") [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable           $ 800,000            
Research and development expense                 138,000 65,000 510,000 835,000
Sponsored Research and Clinical Trial Agreements [Member] | CS1 (MB-104) [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable           $ 2,400,000            
Sponsored Research and Clinical Trial Agreements [Member] | HER2 (MB 103) [Member] | City of Hope National Medical Center ("COH") [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable         $ 29,375              
Research and development expense                 319,000 0 473,000 0
Sponsored Research and Clinical Trial Agreements [Member] | HER2 (MB 103) [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable         $ 3,000,000.0              
Sponsored Research and Clinical Trial Agreements [Member] | PSCA (MB-105) [Member] | City of Hope National Medical Center ("COH") [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable       33,000                
Research and development expense                 23,000 0 69,000 0
Sponsored Research and Clinical Trial Agreements [Member] | PSCA (MB-105) [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable       $ 2,300,000                
Sponsored Research and Clinical Trial Agreements [Member] | CD20 (MB-106) [Member] | Fred Hutchinson Cancer Research Center [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Milestones payable   $ 5,300,000                    
Additional milestone payments     $ 800,000                  
Research and development expense                 492,000 418,000 1,490,000 1,134,000
Sponsored Research and Clinical Trial Agreements [Member] | ST. Jude - XSCID [Member] | St. Jude Children's Research Hospital [Member]                        
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                        
Upfront fees paid $ 1,100,000                      
Research and development expense                 $ 330,000 $ 107,000 $ 610,000 $ 1,665,000