Quarterly report pursuant to Section 13 or 15(d)

Clinical Trial and Sponsored Research Agreements (City of Hope - Sponsored Research and Clinical Trial Agreements) (Narrative) (Details)

v3.23.3
Clinical Trial and Sponsored Research Agreements (City of Hope - Sponsored Research and Clinical Trial Agreements) (Narrative) (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Sep. 08, 2021
Jul. 03, 2017
Nov. 30, 2022
Jan. 31, 2022
Nov. 30, 2020
Oct. 31, 2020
Sep. 30, 2020
Jun. 30, 2020
Feb. 28, 2017
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
License, Clinical Trial and Sponsored Research Agreements                          
Research and development expense                   $ 9,477 $ 15,419 $ 34,313 $ 46,872
Mayo Clinic [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Total reimbursement payments made                   2,200   2,200  
PSCA (MB-105) [Member] | City of Hope National Medical Center ("COH") [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Total reimbursement payments made                   500   500  
HER2 (MB 103) [Member] | City of Hope National Medical Center ("COH") [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Total reimbursement payments made                   3,000   3,000  
CD20 (MB-106) [Member] | Fred Hutchinson Cancer Center [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Total reimbursement payments made                   8,400   8,400  
ST. Jude - XSCID [Member] | St. Jude Children's Research Hospital [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Total reimbursement payments made                   3,500   3,500  
IL13Ra2 CAR and (C134) [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Research and development expense     $ 600     $ 300              
Sponsored Research and Clinical Trial Agreements [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Research and development expense                   364 1,836 3,739 4,884
Sponsored Research and Clinical Trial Agreements [Member] | Mayo Clinic [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Research and development expense                     269 551 731
Sponsored Research and Clinical Trial Agreements [Member] | CD123 (MB-102) [Member] | City of Hope National Medical Center ("COH") [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Contribution per patient                 $ 100        
Research and development expense                   23 63 23 165
Sponsored Research and Clinical Trial Agreements [Member] | IL13Ra2 (MB-101) [Member] | City of Hope National Medical Center ("COH") [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Contribution toward patient costs                 $ 100        
Contribution per patient           100              
Research and development expense                   180 192 817 654
Annual maintenance fee payable           200              
Sponsored Research and Clinical Trial Agreements [Member] | IL13Ra2 (MB-101) [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum                          
License, Clinical Trial and Sponsored Research Agreements                          
Contribution toward patient costs                       200  
Sponsored Research and Clinical Trial Agreements [Member] | CS1 (MB-104) [Member] | City of Hope National Medical Center ("COH") [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Research and development expense                     187 188 287
Total reimbursement payments made                   2,200   2,200  
Sponsored Research and Clinical Trial Agreements [Member] | CS1 (MB-104) [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum                          
License, Clinical Trial and Sponsored Research Agreements                          
Milestones payable               $ 2,400          
Sponsored Research and Clinical Trial Agreements [Member] | PSCA (MB-105) [Member] | City of Hope National Medical Center ("COH") [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Research and development expense                     27 44 77
Sponsored Research and Clinical Trial Agreements [Member] | PSCA (MB-105) [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum                          
License, Clinical Trial and Sponsored Research Agreements                          
Milestones payable           $ 2,300              
Sponsored Research and Clinical Trial Agreements [Member] | HER2 (MB 103) [Member] | City of Hope National Medical Center ("COH") [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Research and development expense                     691 0 1,233
Sponsored Research and Clinical Trial Agreements [Member] | HER2 (MB 103) [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum                          
License, Clinical Trial and Sponsored Research Agreements                          
Milestones payable             $ 3,000            
Sponsored Research and Clinical Trial Agreements [Member] | CD20 (MB-106) [Member] | Fred Hutchinson Cancer Center [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Milestones payable   $ 5,300                      
Additional milestone payments       $ 2,200 $ 1,800                
Contribution toward patient costs         $ 800                
Research and development expense                   142 132 1,239 978
Sponsored Research and Clinical Trial Agreements [Member] | CD20 (MB-106) [Member] | Fred Hutchinson Cancer Center [Member] | Maximum                          
License, Clinical Trial and Sponsored Research Agreements                          
Additional milestone payments       $ 9,300                  
Sponsored Research and Clinical Trial Agreements [Member] | RAG1 SCID (MB-110) [Member] | Leiden University Medical Centre [Member]                          
License, Clinical Trial and Sponsored Research Agreements                          
Agreement term 5 years                        
Research and development expense                   $ 125 $ 92 $ 349 $ 357
Annual maintenance fee payable $ 500