Quarterly report pursuant to Section 13 or 15(d)

Clinical Trial and Sponsored Research Agreements (City of Hope - Sponsored Research and Clinical Trial Agreements) (Narrative) (Details)

v3.23.1
Clinical Trial and Sponsored Research Agreements (City of Hope - Sponsored Research and Clinical Trial Agreements) (Narrative) (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended
Sep. 08, 2021
Jul. 03, 2017
Jan. 31, 2022
Nov. 30, 2020
Oct. 31, 2020
Sep. 30, 2020
Jun. 30, 2020
Feb. 28, 2017
Mar. 31, 2023
Mar. 31, 2022
License, Clinical Trial and Sponsored Research Agreements                    
Research and development expense                 $ 14,000 $ 16,289
Mayo Clinic [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Total reimbursement payments made                 1,900  
PSCA (MB-105) [Member] | City of Hope National Medical Center ("COH") [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Total reimbursement payments made                 400  
CD20 (MB-106) [Member] | Fred Hutchinson Cancer Center [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Total reimbursement payments made                 7,700  
ST. Jude - XSCID [Member] | St. Jude Children's Research Hospital [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Total reimbursement payments made                 3,400  
Sponsored Research and Clinical Trial Agreements [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Research and development expense                 1,742 1,592
Sponsored Research and Clinical Trial Agreements [Member] | Mayo Clinic [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Research and development expense                 275 231
Sponsored Research and Clinical Trial Agreements [Member] | CD123 (MB-102) [Member] | City of Hope National Medical Center ("COH") [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Contribution per patient               $ 100    
Research and development expense                 0 51
Sponsored Research and Clinical Trial Agreements [Member] | IL13Ra2 (MB-101) [Member] | City of Hope National Medical Center ("COH") [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Contribution toward patient costs               $ 100    
Contribution per patient         $ 100          
Research and development expense                 310 228
Annual maintenance fee payable         200          
Sponsored Research and Clinical Trial Agreements [Member] | IL13Ra2 (MB-101) [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum                    
License, Clinical Trial and Sponsored Research Agreements                    
Contribution toward patient costs                 200  
Sponsored Research and Clinical Trial Agreements [Member] | CS1 (MB-104) [Member] | City of Hope National Medical Center ("COH") [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Research and development expense                 50 50
Total reimbursement payments made                 1,900  
Sponsored Research and Clinical Trial Agreements [Member] | CS1 (MB-104) [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum                    
License, Clinical Trial and Sponsored Research Agreements                    
Milestones payable             $ 2,400      
Sponsored Research and Clinical Trial Agreements [Member] | PSCA (MB-105) [Member] | City of Hope National Medical Center ("COH") [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Research and development expense                 22 22
Sponsored Research and Clinical Trial Agreements [Member] | PSCA (MB-105) [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum                    
License, Clinical Trial and Sponsored Research Agreements                    
Milestones payable         $ 2,300          
Sponsored Research and Clinical Trial Agreements [Member] | HER2 (MB 103) [Member] | City of Hope National Medical Center ("COH") [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Research and development expense                 0 271
Sponsored Research and Clinical Trial Agreements [Member] | HER2 (MB 103) [Member] | City of Hope National Medical Center ("COH") [Member] | Maximum                    
License, Clinical Trial and Sponsored Research Agreements                    
Milestones payable           $ 3,000        
Sponsored Research and Clinical Trial Agreements [Member] | CD20 (MB-106) [Member] | Fred Hutchinson Cancer Center [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Milestones payable   $ 5,300                
Additional milestone payments     $ 2,200 $ 1,800            
Contribution toward patient costs       $ 800            
Research and development expense                 554 488
Sponsored Research and Clinical Trial Agreements [Member] | CD20 (MB-106) [Member] | Fred Hutchinson Cancer Center [Member] | Maximum                    
License, Clinical Trial and Sponsored Research Agreements                    
Additional milestone payments     $ 9,300              
Sponsored Research and Clinical Trial Agreements [Member] | ST. Jude - XSCID [Member] | St. Jude Children's Research Hospital [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Research and development expense                 419 124
Sponsored Research and Clinical Trial Agreements [Member] | RAG1 SCID (MB-110) [Member] | Leiden University Medical Centre [Member]                    
License, Clinical Trial and Sponsored Research Agreements                    
Agreement term 5 years                  
Research and development expense                 $ 112 $ 127
Annual maintenance fee payable $ 500