Annual report pursuant to Section 13 and 15(d)

License, Clinical Trial and Sponsored Research Agreements (City of Hope - Licenses) (Narrative) (Details)

v3.21.1
License, Clinical Trial and Sponsored Research Agreements (City of Hope - Licenses) (Narrative) (Details)
 1 Months Ended 12 Months Ended
Feb. 17, 2017
USD ($)
May 31, 2017
USD ($)
item
Feb. 28, 2017
USD ($)
item
Dec. 31, 2020
USD ($)
Dec. 31, 2019
USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Research and development for licenses acquired       $ 10,064,000 $ 6,273,000
License Agreements [Member]          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Research and development for licenses acquired       10,064,000 6,273,000
License Agreements [Member] | CD123 Product or Process [Member] | City of Hope National Medical Center ("COH") [Member]          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Annual maintenance fee payable     $ 25,000    
Milestones payable     $ 14,500,000    
Research and development for licenses acquired       334,000 250,000
License Agreements [Member] | CS1 Product or Process [Member] | City of Hope National Medical Center ("COH") [Member]          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Annual maintenance fee payable   $ 50,000      
Upfront fees paid   $ 600,000      
Number of milestones | item   10      
Milestones payable   $ 14,900,000      
Research and development for licenses acquired       200,000 200,000
License Agreements [Member] | IL13Ra2 Product [Member] | City of Hope National Medical Center ("COH") [Member]          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Number of milestones | item     8    
Milestones payable     $ 14,500,000    
Research and development for licenses acquired       333,000 0
License Agreements [Member] | IV/ICV Product or Process [Member] | City of Hope National Medical Center ("COH") [Member]          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Upfront fees paid $ 100,000        
Milestones payable 100,000        
Research and development for licenses acquired $ 0        
License Agreements [Member] | Spacer Product or Process [Member] | City of Hope National Medical Center ("COH") [Member]          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Research and development for licenses acquired       333,000 0
License Agreements [Member] | PSCA Product or Process [Member] | City of Hope National Medical Center ("COH") [Member]          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Annual maintenance fee payable   50,000      
Upfront fees paid   $ 300,000      
Number of milestones | item   10      
Milestones payable   $ 14,900,000      
Research and development for licenses acquired       200,000 200,000
License Agreements [Member] | HER2 Product or Process [Member] | City of Hope National Medical Center ("COH") [Member]          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Annual maintenance fee payable   50,000      
Upfront fees paid   $ 600,000      
Number of milestones | item   10      
Milestones payable   $ 14,900,000      
Research and development for licenses acquired       $ 500,000 $ 0