Annual report pursuant to Section 13 and 15(d)

License, Clinical Trial and Sponsored Research Agreements (City of Hope - Licenses) (Narrative) (Details)

v3.23.1
License, Clinical Trial and Sponsored Research Agreements (City of Hope - Licenses) (Narrative) (Details)
 1 Months Ended 12 Months Ended
Sep. 08, 2021
USD ($)
Apr. 01, 2021
USD ($)
Milestone
Aug. 23, 2019
USD ($)
item
May 31, 2017
USD ($)
item
Feb. 28, 2017
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
License, Clinical Trial and Sponsored Research Agreements              
Research and development - licenses acquired           $ 1,474,000 $ 5,842,000
Mayo Clinic [Member]              
License, Clinical Trial and Sponsored Research Agreements              
Upfront fees paid   $ 800,000          
License Agreements [Member]              
License, Clinical Trial and Sponsored Research Agreements              
Research and development - licenses acquired           1,474,000 5,842,000
License Agreements [Member] | CSL Behring (Calimmune) [Member]              
License, Clinical Trial and Sponsored Research Agreements              
Upfront fees paid     $ 200,000        
Number of milestones | item     3        
Milestones payable     $ 1,200,000        
Research and development - licenses acquired           40,000 30,000
License Agreements [Member] | Leiden University Medical Centre [Member]              
License, Clinical Trial and Sponsored Research Agreements              
Upfront fees paid $ 400,000         0  
Milestones payable $ 31,000,000            
Research and development - licenses acquired           0 350,000
Non-refundable milestone payments             400,000
License Agreements [Member] | Mayo Clinic [Member]              
License, Clinical Trial and Sponsored Research Agreements              
Annual maintenance fee payable   $ 25,000          
Upfront fees paid           0  
Number of milestones | Milestone   11          
Milestones payable   $ 92,600,000          
Research and development - licenses acquired           0 750,000
License Agreements [Member] | CD123 (MB-102) [Member] | City of Hope National Medical Center ("COH") [Member]              
License, Clinical Trial and Sponsored Research Agreements              
Annual maintenance fee payable         $ 25,000    
Milestones payable         14,500,000    
Research and development - licenses acquired           0 250,000
Non-refundable milestone payments           0  
License Agreements [Member] | IV/ICV Product or Process [Member] | City of Hope National Medical Center ("COH") [Member]              
License, Clinical Trial and Sponsored Research Agreements              
Annual maintenance fee payable         25,000    
Upfront fees paid         100,000    
Milestones payable         $ 100,000    
Research and development - licenses acquired           125,000 0
Non-refundable milestone payments           100,000 0
License Agreements [Member] | PSCA (MB-105) [Member] | City of Hope National Medical Center ("COH") [Member]              
License, Clinical Trial and Sponsored Research Agreements              
Annual maintenance fee payable       $ 50,000      
Upfront fees paid       $ 300,000      
Number of milestones | item       10      
Milestones payable       $ 14,900,000      
Research and development - licenses acquired           0 250,000
Non-refundable milestone payments           0 300,000
License Agreements [Member] | HER2 (MB 103) [Member] | City of Hope National Medical Center ("COH") [Member]              
License, Clinical Trial and Sponsored Research Agreements              
Annual maintenance fee payable       50,000      
Upfront fees paid       $ 600,000      
Number of milestones | item       10      
Milestones payable       $ 14,900,000      
Research and development - licenses acquired           200,000 0
Non-refundable milestone payments           $ 200,000 $ 0