Annual report [Section 13 and 15(d), not S-K Item 405]

License, Clinical Trial and Sponsored Research Agreements (Ongoing, Terminated Clinical Trial and Sponsored Research Agreements) (Narrative) (Details)

v3.25.1
License, Clinical Trial and Sponsored Research Agreements (Ongoing, Terminated Clinical Trial and Sponsored Research Agreements) (Narrative) (Details) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Jul. 03, 2017
Jun. 30, 2024
Apr. 30, 2024
Nov. 30, 2022
Jan. 31, 2022
Nov. 30, 2020
Oct. 31, 2020
Feb. 28, 2017
Dec. 31, 2024
Dec. 31, 2023
License, Clinical Trial and Sponsored Research Agreements                    
Research and development expense                 $ 7,557 $ 40,513
Research and development                    
License, Clinical Trial and Sponsored Research Agreements                    
Forgiveness of all amounts previously owed                 $ 900  
Mayo Clinic                    
License, Clinical Trial and Sponsored Research Agreements                    
Forgiveness of all amounts previously owed   $ 300                
St. Jude Children's Research Hospital - XSCID                    
License, Clinical Trial and Sponsored Research Agreements                    
Forgiveness of all amounts previously owed     $ 600              
IL13Ra2 CAR and (C134)                    
License, Clinical Trial and Sponsored Research Agreements                    
Research and development expense       $ 600     $ 300      
Clinical trial and sponsored research agreements | IL13R2 (MB-101) | City of Hope National Medical Center                    
License, Clinical Trial and Sponsored Research Agreements                    
Contribution toward patient costs               $ 100    
Contribution per patient             100      
Annual maintenance fee payable             $ 200      
Clinical trial and sponsored research agreements | CD20 (MB-106) | Fred Hutchinson Cancer Center                    
License, Clinical Trial and Sponsored Research Agreements                    
Contribution toward patient costs           $ 800        
Milestones payable $ 5,300                  
Additional milestone payments         $ 2,200 $ 1,800        
Clinical trial and sponsored research agreements | CD20 (MB-106) | Fred Hutchinson Cancer Center | Maximum                    
License, Clinical Trial and Sponsored Research Agreements                    
Additional milestone payments         $ 9,300